Which Of The Following Is An Environmental Condition That Could Influence Cell Differentiation? (2024)

1. Environmental Influences on Gene Expression - Nature

  • One major internal environmental influence that affects gene expression is gender, as is the case with sex-influenced and sex-limited traits. Similarly, drugs, ...

  • Internal and external environmental factors, like gender and temperature, influence gene expression.

2. Environmental Physical Cues Determine the Lineage ... - NCBI

  • Physical cues of cellular environment affect cell fate and differentiation. For example, an environment with high stiffness drives mesenchymal stem cells ...

  • Physical cues of cellular environment affect cell fate and differentiation. For example, an environment with high stiffness drives mesenchymal stem cells (MSCs) to undergo osteogenic differentiation, while low stiffness leads to lipogenic differentiation. ...

3. Factors and molecules that could impact cell differentiation in ... - NCBI

  • The epigenetic modifications established during cellular differentiation are a major factor determining this low efficiency as they act as epigenetic barriers ...

  • Somatic cell nuclear transfer is a technique to create an embryo using an enucleated oocyte and a donor nucleus. Nucleus of somatic cells must be reprogrammed in order to participate in normal development within an enucleated egg. Reprogramming refers ...

4. Stem cells: past, present, and future

  • 26 Feb 2019 · Derivation methods and the utilization of culturing media are crucial to set proper environmental conditions for controlled differentiation.

  • In recent years, stem cell therapy has become a very promising and advanced scientific research topic. The development of treatment methods has evoked great expectations. This paper is a review focused on the discovery of different stem cells and the potential therapies based on these cells. The genesis of stem cells is followed by laboratory steps of controlled stem cell culturing and derivation. Quality control and teratoma formation assays are important procedures in assessing the properties of the stem cells tested. Derivation methods and the utilization of culturing media are crucial to set proper environmental conditions for controlled differentiation. Among many types of stem tissue applications, the use of graphene scaffolds and the potential of extracellular vesicle-based therapies require attention due to their versatility. The review is summarized by challenges that stem cell therapy must overcome to be accepted worldwide. A wide variety of possibilities makes this cutting edge therapy a turning point in modern medicine, providing hope for untreatable diseases.

5. Functional dynamic genetic effects on gene regulation are specific ... - eLife

  • 14 May 2021 · Genetic effects on gene expression and splicing can be modulated by cellular and environmental factors; yet interactions between genotypes, ...

  • The activity of the genes in a cell depends on the type of cell they are in, the interactions with other genes, the environment and genetics. Active genes produce a greater number of mRNA molecules, which act as messenger molecules to instruct the cell to produce proteins. The amount of mRNA molecules in cells can be measured to assess the levels of gene activity. Genes produce mRNAs through a process called transcription, and the collection of all the mRNA molecules in a cell is called the transcriptome. Cells obtained from human samples can be grown in the lab under different conditions, and this can be used to transform them into different types of cells. These cells can then be exposed to different treatments – such as specific chemicals – to understand how the environment affects them. Cells derived from different people may respond differently to the same treatment based on their unique genetics. Exposing different types of cells from many people to different treatments can help explain how genetics, the environment and cell type affect gene activity. Findley et al. grew three different types of cells from six different people in the lab. The cells were exposed to 28 different treatments, which reflect different environmental changes. Studying all these different factors together allowed Findley et al. to understand how genetics, cell type and environment affect the activity of over 53,000 genes. Around half of the effects due to an interaction between genetics and the environment and had not been seen in other larger studies of the transcriptome. Many of these newly observed changes are in genes that have connections to different diseases, including heart disease. The results of Findley et al. provide evidence indicating to which extent lifestyle and the environment can interact with an individual’s genetic makeup to impact gene activity and long-term health. The more researchers can understand these factors, the more useful they can be in helping to predict, detect and treat illnesses. The findings also show how genes and the environment interact, which may be relevant to understanding disease development. There is more work to be done to understand a wider range of environmental factors across more cell types. It will also be important to establish how this work on cells grown in the lab translates to human health.

6. Cell Growth and Differentiation - Oxford Academic

  • Similarly, differentiation of a cell is influenced by its genetic composition and the environment that surrounds it. This chapter begins with a discussion of ...

  • Abstract. The expansion in size of a region of tissue, often called growth, is critical to embryonic development and tissue repair. Growth of a tissue most ofte

7. How to fit in: The learning principles of cell differentiation - PLOS

  • Cell differentiation in multicellular organisms requires cells to respond to complex combinations of extracellular cues, such as morphogen concentrations.

  • Author summary In organisms composed of many cell types, the differentiation of cells relies on their ability to respond to complex extracellular cues, such as morphogen concentrations, a phenomenon known as cell plasticity. Although cell plasticity plays a crucial role in development and evolution, it is not clear how, and if, cell plasticity can enhance adaptation to a novel environment and/or facilitate robust developmental processes. In some models, the relationships between the environmental cues (inputs) and the phenotypic responses (outputs) are conceptualised as one-to-one (i.e. simple ‘reaction norms’); whereas the phenotype of plastic cells commonly depends on several simultaneous inputs (i.e. many-to-one, multi-dimensional reaction norms). One alternative is the use of a gene-regulatory network (GRN) models that allow for much more general responses; but this can make analysis difficult. In this work we use a theoretical framework based on logical functions and learning theory to characterize such multi-dimensional reaction norms produced by GRNs. This allows us to reveal a strong and previously unnoticed bias towards the acquisition of simple forms of cell plasticity, which increases their ability to adapt to novel environments. Recognising this bias helps us to understand when the evolution of cell plasticity will increase the ability of plastic cells to adapt to novel environments, to respond appropriately to complex extracellular cues and to enhance developmental robustness. Since this set of properties are required for the evolution of multicellularity, our approach can also contribute to our understanding of this evolutionary transition.

8. Solved: Which of the following is an environmental condition[algebra]

  • Answer to Which of the following is an environmental condition that could influence cell differentiation? Exposure to high temperature Size of the cell ...

  • Answer to Which of the following is an environmental condition that could influence cell differentiation? Exposure to high temperature Size of the cell Mutation

9. Stem cells: What they are and what they do - Mayo Clinic

  • These daughter cells become either new stem cells or specialized cells (differentiation) ... cells will differentiate into the specific cell types desired.

  • Get answers about where stem cells come from, why they're important for understanding and treating disease, and the ethics of using them.

10. Environmental Factors That Influence Stem Cell Migration: An “Electric ...

  • Electrical stimulation can also affect the differentiation profile of NPCs. In ... Cell-specific factors such as cell type and differentiation state, along ...

  • Environmental Stimulus of Electric Fields on Stem Cell Migration. The movement of cells in response to electric potential gradients is called galvanotaxis. In vivo galvanotaxis, powered by endogenous electric fields (EFs), plays a critical role during development and wound healing. This review aims to provide a perspective on how stem cells transduce EFs into directed migration and an understanding of the current literature relating to the mechanisms by which cells sense and transduce EFs. We will comment on potential EF-based regenerative medicine therapeutics.

11. Factors Involved in Cell Differentiation - Sciencing

  • 23 Apr 2019 · Factors that affect cell specialization and cell differentiation include internal influences and environmental conditions.

  • Factors that affect cell specialization and cell differentiation include internal influences and environmental conditions. Defective DNA and disease can block the cell signaling that guides cell differentiation. Chemicals and drugs from external sources can disrupt differentiation as well.

12. What is Epigenetics? - CDC

  • While genetic changes can alter which protein is made, epigenetic changes affect gene expression to turn genes “on” and “off.” Since your environment and ...

  • Epigenetics is the study of how your behaviors and environment can cause changes that affect the way your genes work.

13. How cells respond to environmental cues – insights from bio ...

  • 1 Jan 2017 · ... cell differentiation, has been drawn from these observations. In ... cellular property or differentiation or polarization program could thus ...

  • Summary: Cells are sensitive to some biophysical aspects of the environment. This Commentary reviews how bio-functionalized substrates can be used to analyze how cells sense and interact with their environment.

Which Of The Following Is An Environmental Condition That Could Influence Cell Differentiation? (2024)
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